We design peptides for the benefit of humanity

Our impact in numbers

  • 3 billion
    Peptides Discovered

    Novel sequences explored computationally.

  • 6,000
    Peptides Synthesized

    Successfully produced in our automated synthesis pipeline.

  • 100
    Peptides Validated Preclinically

    Molecules advanced to in vivo validation.

Research Area

Medicine

Peptide therapeutics for what current drugs cannot treat: resistant infections, cancer, and beyond.

Sustainability

Developing peptides for crop protection, rare earth recovery, carbon capture, and environmental remediation.

Materials

Engineering peptide-based organic semiconductors and materials for batteries, bioelectronics, drug delivery, tissue repair, and beyond.

Technologies

Integrating AI, chemistry, and high-throughput experimentation to accelerate peptide discovery, design, and validation—and build the next generation of peptide technologies.

Latest updates

What’s Peptide Design?

Peptides are short chains of amino acids. They're large enough to act precisely on biological targets and small enough to make by chemistry.

Peptide design means creating new molecules with a purpose. We use AI to discover and propose sequences, chemistry to build and refine them, and experiments to test how they perform. Each round of testing guides the next round of design. The goal is to develop peptides with the properties needed to treat disease, build new materials, protect crops, and more.

Center for Peptide Design

A global hub for peptide design

We bring together chemists, biologists, engineers, clinicians and computer scientists from around the world to work as one team. Here, AI, chemistry and biology meet at the same bench. Ideas move from model to molecule to impact faster than any single discipline could manage alone.

We welcome researchers, students and partners from every country and every field who want to design peptides for the benefit of humanity.

What peptides can do

Peptides are among the smallest functional molecules of life. In nature, they fight infections, target tumors, boost the immune system, regulate sleep and shape how the brain works and behaves.

Imagine if we could design them.

That's what we do. We use AI to explore sequences evolution never tried and chemistry to build them, and we test each one. The result is peptides made on purpose to heal, protect and build.

From discovery to impact

Designed at the Center, translated through the companies it creates. Our first spinout sits a short walk away, across the Schuylkill.

Center forPeptide Design

Johnson Pavilion · University of Pennsylvania
3610 Hamilton Walk, Philadelphia, PA 19104

RESEARCH HUB

Peptaris (opens in a new tab)

AI-designed peptide therapeutics

Lilly Gateway Labs · 2300 Market St, Philadelphia, PA 19103
Founded 2025 · peptaris.com (opens in a new tab)

PENN STARTUP FUND 2026

Map tiles © Esri, HERE, Garmin and OpenStreetMap contributors (opens in a new tab).